{"id":392,"date":"2019-12-05T02:10:09","date_gmt":"2019-12-05T02:10:09","guid":{"rendered":"https:\/\/drnat.com\/nd\/?p=392"},"modified":"2019-12-05T02:27:51","modified_gmt":"2019-12-05T02:27:51","slug":"prp-and-elbow","status":"publish","type":"post","link":"https:\/\/drnat.com\/nd\/prp-and-elbow\/","title":{"rendered":"Ongoing positive effect of\u00a0platelet-rich plasma\u00a0versus corticosteroid injection in lateral epicondylitis: a double- blind randomized controlled trial with 2-year follow-up."},"content":{"rendered":"

Am J Sports Med.<\/a> 2011 Jun;39(6):1200-8. Epub 2011 Mar 21.<\/p>\n

Abstract<\/h3>\n

BACKGROUND:<\/h4>\n

Platelet-rich plasma (PRP) has been shown to be a general stimulation for repair and 1-year results showed promising success percentages.<\/p>\n

PURPOSE:<\/h4>\n

This trial was undertaken to determine the effectiveness of PRP compared with corticosteroid injections in patients with chronic lateral epicondylitis with a 2-year follow-up.<\/p>\n

STUDY DESIGN:<\/h4>\n

Randomized controlled trial; Level of evidence, 1.<\/p>\n

METHODS:<\/h4>\n

The trial was conducted in 2 Dutch teaching hospitals. One hundred patients with chronic lateral epicondylitis were randomly assigned to a leukocyte-enriched PRP group (n = 51) or the corticosteroid group (n = 49). Randomization and allocation to the trial group were carried out by a central computer system. Patients received either a corticosteroid injection or an autologous platelet concentrate injection through a peppering needling technique. The primary analysis included visual analog scale (VAS) pain scores and Disabilities of the Arm, Shoulder and Hand (DASH) outcome scores.<\/p>\n

RESULTS:<\/h4>\n

The PRP group was more often successfully treated than the corticosteroid group (P < .0001). Success was defined as a reduction of 25% on VAS or DASH scores without a reintervention after 2 years. When baseline VAS and DASH scores were compared with the scores at 2-year follow-up, both groups significantly improved across time (intention-to-treat principle). However, the DASH scores of the corticosteroid group returned to baseline levels, while those of the PRP group significantly improved (as-treated principle). There were no complications related to the use of PRP.<\/p>\n

CONCLUSION:<\/h4>\n

Treatment of patients with chronic lateral epicondylitis with PRP reduces pain and increases function significantly, exceeding the effect of corticosteroid injection even after a follow-up of 2 years. Future decisions for application of PRP for lateral epicondylitis should be confirmed by further follow-up from this trial and should take into account possible costs and harms as well as benefits.<\/p>\n","protected":false},"excerpt":{"rendered":"

Am J Sports Med. 2011 Jun;39(6):1200-8. Epub 2011 Mar 21. Abstract BACKGROUND: Platelet-rich plasma (PRP) has been shown to be a general stimulation for repair and 1-year results showed promising success percentages. PURPOSE: This trial was undertaken to determine the effectiveness of PRP compared with corticosteroid injections in patients with chronic lateral epicondylitis with a 2-year […]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","ngg_post_thumbnail":0,"footnotes":""},"categories":[8,9],"tags":[],"yoast_head":"\nOngoing positive effect of\u00a0platelet-rich plasma\u00a0versus corticosteroid injection in lateral epicondylitis: a double- blind randomized controlled trial with 2-year follow-up. - Dr. Nathan Ehrlich, N.D.<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/drnat.com\/nd\/prp-and-elbow\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"Ongoing positive effect of\u00a0platelet-rich plasma\u00a0versus corticosteroid injection in lateral epicondylitis: a double- blind randomized controlled trial with 2-year follow-up. - Dr. Nathan Ehrlich, N.D.\" \/>\n<meta property=\"og:description\" content=\"Am J Sports Med. 2011 Jun;39(6):1200-8. 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