{"id":372,"date":"2019-12-05T02:04:11","date_gmt":"2019-12-05T02:04:11","guid":{"rendered":"https:\/\/drnat.com\/nd\/?p=372"},"modified":"2019-12-05T02:04:11","modified_gmt":"2019-12-05T02:04:11","slug":"prp-and-knee-6","status":"publish","type":"post","link":"https:\/\/drnat.com\/nd\/prp-and-knee-6\/","title":{"rendered":"PRP and KNEE"},"content":{"rendered":"<p><a title=\"Knee surgery, sports traumatology, arthroscopy : official journal of the ESSKA.\" href=\"x-msg:\/\/129\/#\">Knee&nbsp;Surg Sports Traumatol Arthrosc.<\/a> 2010 Apr;18(4):472-9. Epub 2009 Oct 17.<\/p>\n<h1><a href=\"x-msg:\/\/129\/pubmed\/19838676\">Platelet-rich plasma: intra-articular&nbsp;knee&nbsp;injections<\/a><\/h1>\n<h1><a href=\"x-msg:\/\/129\/pubmed\/19838676\"> produced favorable results on degenerative cartilage lesions.<\/a><\/h1>\n<p><a href=\"x-msg:\/\/129\/pubmed?term=%22Kon%20E%22%5BAuthor%5D\">Kon E<\/a>,&nbsp;<a href=\"x-msg:\/\/129\/pubmed?term=%22Buda%20R%22%5BAuthor%5D\">Buda R<\/a>,&nbsp;<a href=\"x-msg:\/\/129\/pubmed?term=%22Filardo%20G%22%5BAuthor%5D\">Filardo G<\/a>,&nbsp;<a href=\"x-msg:\/\/129\/pubmed?term=%22Di%20Martino%20A%22%5BAuthor%5D\">Di Martino A<\/a>,&nbsp;<a href=\"x-msg:\/\/129\/pubmed?term=%22Timoncini%20A%22%5BAuthor%5D\">Timoncini A<\/a>,&nbsp;<a href=\"x-msg:\/\/129\/pubmed?term=%22Cenacchi%20A%22%5BAuthor%5D\">Cenacchi A<\/a>,&nbsp;<a href=\"x-msg:\/\/129\/pubmed?term=%22Fornasari%20PM%22%5BAuthor%5D\">Fornasari PM<\/a>,&nbsp;<a href=\"x-msg:\/\/129\/pubmed?term=%22Giannini%20S%22%5BAuthor%5D\">Giannini S<\/a>,&nbsp;<a href=\"x-msg:\/\/129\/pubmed?term=%22Marcacci%20M%22%5BAuthor%5D\">Marcacci M<\/a>.<\/p>\n<p>Department of Orthopaedic and Sports Trauma, Rizzoli Orthopaedic Institute, Bologna, Italy.&nbsp;<a href=\"mailto:e.kon@biomec.ior.it\">e.kon@biomec.ior.it<\/a><\/p>\n<h3>Abstract<\/h3>\n<p>Platelet-rich plasma (PRP) is a natural concentrate of autologous blood growth factors experimented in different fields of medicine in order to test its potential to enhance tissue regeneration. The aim of our study is to explore this novel approach to treat degenerative lesions of articular cartilage of the&nbsp;knee. One hundred consecutive patients, affected by chronic degenerative condition of the&nbsp;knee, were treated with&nbsp;PRP&nbsp;intra-articular injections (115 knees treated). The procedure consisted of 150-ml of venous blood collected and twice centrifugated: 3&nbsp;PRP&nbsp;units of 5 ml each were used for the injections. Patients were clinically prospectively evaluated before and at the end of the treatment, and at 6 and 12 months follow-up. IKDC, objective and subjective, and EQ VAS were used for clinical evaluation. Statistical analysis was performed to evaluate the significance of sex, age, grade of&nbsp;OA&nbsp;and BMI. A statistically significant improvement of all clinical scores was obtained from the basal evaluation to the end of the therapy and at 6-12 months follow-up (P &lt; 0.0005). The results remained stable from the end of the therapy to 6 months follow up, whereas they became significantly worse at 12 months follow up (P = 0.02), even if still significantly higher respect to the basal level (P &lt; 0.0005). The preliminary results indicate that the treatment with&nbsp;PRP&nbsp;injections is safe and has the potential to reduce pain and improve&nbsp;knee&nbsp;function and quality of live in younger patients with low degree of articular degeneration.<\/p>\n","protected":false},"excerpt":{"rendered":"<p>Knee&nbsp;Surg Sports Traumatol Arthrosc. 2010 Apr;18(4):472-9. Epub 2009 Oct 17. Platelet-rich plasma: intra-articular&nbsp;knee&nbsp;injections produced favorable results on degenerative cartilage lesions. Kon E,&nbsp;Buda R,&nbsp;Filardo G,&nbsp;Di Martino A,&nbsp;Timoncini A,&nbsp;Cenacchi A,&nbsp;Fornasari PM,&nbsp;Giannini S,&nbsp;Marcacci M. Department of Orthopaedic and Sports Trauma, Rizzoli Orthopaedic Institute, Bologna, Italy.&nbsp;e.kon@biomec.ior.it Abstract Platelet-rich plasma (PRP) is a natural concentrate of autologous blood growth factors [&hellip;]<\/p>\n","protected":false},"author":1,"featured_media":0,"comment_status":"open","ping_status":"open","sticky":false,"template":"","format":"standard","meta":{"_et_pb_use_builder":"","_et_pb_old_content":"","_et_gb_content_width":"","ngg_post_thumbnail":0,"footnotes":""},"categories":[8,7],"tags":[],"yoast_head":"<!-- This site is optimized with the Yoast SEO plugin v22.9 - https:\/\/yoast.com\/wordpress\/plugins\/seo\/ -->\n<title>PRP and KNEE - Dr. Nathan Ehrlich, N.D.<\/title>\n<meta name=\"robots\" content=\"index, follow, max-snippet:-1, max-image-preview:large, max-video-preview:-1\" \/>\n<link rel=\"canonical\" href=\"https:\/\/drnat.com\/nd\/prp-and-knee-6\/\" \/>\n<meta property=\"og:locale\" content=\"en_US\" \/>\n<meta property=\"og:type\" content=\"article\" \/>\n<meta property=\"og:title\" content=\"PRP and KNEE - Dr. Nathan Ehrlich, N.D.\" \/>\n<meta property=\"og:description\" content=\"Knee&nbsp;Surg Sports Traumatol Arthrosc. 2010 Apr;18(4):472-9. Epub 2009 Oct 17. Platelet-rich plasma: intra-articular&nbsp;knee&nbsp;injections produced favorable results on degenerative cartilage lesions. Kon E,&nbsp;Buda R,&nbsp;Filardo G,&nbsp;Di Martino A,&nbsp;Timoncini A,&nbsp;Cenacchi A,&nbsp;Fornasari PM,&nbsp;Giannini S,&nbsp;Marcacci M. Department of Orthopaedic and Sports Trauma, Rizzoli Orthopaedic Institute, Bologna, Italy.&nbsp;e.kon@biomec.ior.it Abstract Platelet-rich plasma (PRP) is a natural concentrate of autologous blood growth factors [&hellip;]\" \/>\n<meta property=\"og:url\" content=\"https:\/\/drnat.com\/nd\/prp-and-knee-6\/\" \/>\n<meta property=\"og:site_name\" content=\"Dr. Nathan Ehrlich, N.D.\" \/>\n<meta property=\"article:published_time\" content=\"2019-12-05T02:04:11+00:00\" \/>\n<meta name=\"author\" content=\"NAt\" \/>\n<meta name=\"twitter:card\" content=\"summary_large_image\" \/>\n<meta name=\"twitter:label1\" content=\"Written by\" \/>\n\t<meta name=\"twitter:data1\" content=\"NAt\" \/>\n\t<meta name=\"twitter:label2\" content=\"Est. reading time\" \/>\n\t<meta name=\"twitter:data2\" content=\"2 minutes\" \/>\n<script type=\"application\/ld+json\" class=\"yoast-schema-graph\">{\"@context\":\"https:\/\/schema.org\",\"@graph\":[{\"@type\":\"WebPage\",\"@id\":\"https:\/\/drnat.com\/nd\/prp-and-knee-6\/\",\"url\":\"https:\/\/drnat.com\/nd\/prp-and-knee-6\/\",\"name\":\"PRP and KNEE - Dr. Nathan Ehrlich, N.D.\",\"isPartOf\":{\"@id\":\"https:\/\/drnat.com\/nd\/#website\"},\"datePublished\":\"2019-12-05T02:04:11+00:00\",\"dateModified\":\"2019-12-05T02:04:11+00:00\",\"author\":{\"@id\":\"https:\/\/drnat.com\/nd\/#\/schema\/person\/0fb549d14b7bb58de157ffb3998db3dc\"},\"breadcrumb\":{\"@id\":\"https:\/\/drnat.com\/nd\/prp-and-knee-6\/#breadcrumb\"},\"inLanguage\":\"en-US\",\"potentialAction\":[{\"@type\":\"ReadAction\",\"target\":[\"https:\/\/drnat.com\/nd\/prp-and-knee-6\/\"]}]},{\"@type\":\"BreadcrumbList\",\"@id\":\"https:\/\/drnat.com\/nd\/prp-and-knee-6\/#breadcrumb\",\"itemListElement\":[{\"@type\":\"ListItem\",\"position\":1,\"name\":\"Home\",\"item\":\"https:\/\/drnat.com\/nd\/\"},{\"@type\":\"ListItem\",\"position\":2,\"name\":\"PRP and KNEE\"}]},{\"@type\":\"WebSite\",\"@id\":\"https:\/\/drnat.com\/nd\/#website\",\"url\":\"https:\/\/drnat.com\/nd\/\",\"name\":\"Dr. Nathan Ehrlich, N.D.\",\"description\":\"Physician \/ Musician\",\"potentialAction\":[{\"@type\":\"SearchAction\",\"target\":{\"@type\":\"EntryPoint\",\"urlTemplate\":\"https:\/\/drnat.com\/nd\/?s={search_term_string}\"},\"query-input\":\"required name=search_term_string\"}],\"inLanguage\":\"en-US\"},{\"@type\":\"Person\",\"@id\":\"https:\/\/drnat.com\/nd\/#\/schema\/person\/0fb549d14b7bb58de157ffb3998db3dc\",\"name\":\"NAt\",\"image\":{\"@type\":\"ImageObject\",\"inLanguage\":\"en-US\",\"@id\":\"https:\/\/drnat.com\/nd\/#\/schema\/person\/image\/\",\"url\":\"https:\/\/secure.gravatar.com\/avatar\/68a842d3599799d23ca9a8930a405aa1?s=96&d=mm&r=g\",\"contentUrl\":\"https:\/\/secure.gravatar.com\/avatar\/68a842d3599799d23ca9a8930a405aa1?s=96&d=mm&r=g\",\"caption\":\"NAt\"},\"url\":\"https:\/\/drnat.com\/nd\/author\/NAt\/\"}]}<\/script>\n<!-- \/ Yoast SEO plugin. -->","yoast_head_json":{"title":"PRP and KNEE - Dr. Nathan Ehrlich, N.D.","robots":{"index":"index","follow":"follow","max-snippet":"max-snippet:-1","max-image-preview":"max-image-preview:large","max-video-preview":"max-video-preview:-1"},"canonical":"https:\/\/drnat.com\/nd\/prp-and-knee-6\/","og_locale":"en_US","og_type":"article","og_title":"PRP and KNEE - Dr. Nathan Ehrlich, N.D.","og_description":"Knee&nbsp;Surg Sports Traumatol Arthrosc. 2010 Apr;18(4):472-9. Epub 2009 Oct 17. Platelet-rich plasma: intra-articular&nbsp;knee&nbsp;injections produced favorable results on degenerative cartilage lesions. Kon E,&nbsp;Buda R,&nbsp;Filardo G,&nbsp;Di Martino A,&nbsp;Timoncini A,&nbsp;Cenacchi A,&nbsp;Fornasari PM,&nbsp;Giannini S,&nbsp;Marcacci M. Department of Orthopaedic and Sports Trauma, Rizzoli Orthopaedic Institute, Bologna, Italy.&nbsp;e.kon@biomec.ior.it Abstract Platelet-rich plasma (PRP) is a natural concentrate of autologous blood growth factors [&hellip;]","og_url":"https:\/\/drnat.com\/nd\/prp-and-knee-6\/","og_site_name":"Dr. Nathan Ehrlich, N.D.","article_published_time":"2019-12-05T02:04:11+00:00","author":"NAt","twitter_card":"summary_large_image","twitter_misc":{"Written by":"NAt","Est. reading time":"2 minutes"},"schema":{"@context":"https:\/\/schema.org","@graph":[{"@type":"WebPage","@id":"https:\/\/drnat.com\/nd\/prp-and-knee-6\/","url":"https:\/\/drnat.com\/nd\/prp-and-knee-6\/","name":"PRP and KNEE - Dr. Nathan Ehrlich, N.D.","isPartOf":{"@id":"https:\/\/drnat.com\/nd\/#website"},"datePublished":"2019-12-05T02:04:11+00:00","dateModified":"2019-12-05T02:04:11+00:00","author":{"@id":"https:\/\/drnat.com\/nd\/#\/schema\/person\/0fb549d14b7bb58de157ffb3998db3dc"},"breadcrumb":{"@id":"https:\/\/drnat.com\/nd\/prp-and-knee-6\/#breadcrumb"},"inLanguage":"en-US","potentialAction":[{"@type":"ReadAction","target":["https:\/\/drnat.com\/nd\/prp-and-knee-6\/"]}]},{"@type":"BreadcrumbList","@id":"https:\/\/drnat.com\/nd\/prp-and-knee-6\/#breadcrumb","itemListElement":[{"@type":"ListItem","position":1,"name":"Home","item":"https:\/\/drnat.com\/nd\/"},{"@type":"ListItem","position":2,"name":"PRP and KNEE"}]},{"@type":"WebSite","@id":"https:\/\/drnat.com\/nd\/#website","url":"https:\/\/drnat.com\/nd\/","name":"Dr. Nathan Ehrlich, N.D.","description":"Physician \/ Musician","potentialAction":[{"@type":"SearchAction","target":{"@type":"EntryPoint","urlTemplate":"https:\/\/drnat.com\/nd\/?s={search_term_string}"},"query-input":"required name=search_term_string"}],"inLanguage":"en-US"},{"@type":"Person","@id":"https:\/\/drnat.com\/nd\/#\/schema\/person\/0fb549d14b7bb58de157ffb3998db3dc","name":"NAt","image":{"@type":"ImageObject","inLanguage":"en-US","@id":"https:\/\/drnat.com\/nd\/#\/schema\/person\/image\/","url":"https:\/\/secure.gravatar.com\/avatar\/68a842d3599799d23ca9a8930a405aa1?s=96&d=mm&r=g","contentUrl":"https:\/\/secure.gravatar.com\/avatar\/68a842d3599799d23ca9a8930a405aa1?s=96&d=mm&r=g","caption":"NAt"},"url":"https:\/\/drnat.com\/nd\/author\/NAt\/"}]}},"_links":{"self":[{"href":"https:\/\/drnat.com\/nd\/wp-json\/wp\/v2\/posts\/372"}],"collection":[{"href":"https:\/\/drnat.com\/nd\/wp-json\/wp\/v2\/posts"}],"about":[{"href":"https:\/\/drnat.com\/nd\/wp-json\/wp\/v2\/types\/post"}],"author":[{"embeddable":true,"href":"https:\/\/drnat.com\/nd\/wp-json\/wp\/v2\/users\/1"}],"replies":[{"embeddable":true,"href":"https:\/\/drnat.com\/nd\/wp-json\/wp\/v2\/comments?post=372"}],"version-history":[{"count":1,"href":"https:\/\/drnat.com\/nd\/wp-json\/wp\/v2\/posts\/372\/revisions"}],"predecessor-version":[{"id":373,"href":"https:\/\/drnat.com\/nd\/wp-json\/wp\/v2\/posts\/372\/revisions\/373"}],"wp:attachment":[{"href":"https:\/\/drnat.com\/nd\/wp-json\/wp\/v2\/media?parent=372"}],"wp:term":[{"taxonomy":"category","embeddable":true,"href":"https:\/\/drnat.com\/nd\/wp-json\/wp\/v2\/categories?post=372"},{"taxonomy":"post_tag","embeddable":true,"href":"https:\/\/drnat.com\/nd\/wp-json\/wp\/v2\/tags?post=372"}],"curies":[{"name":"wp","href":"https:\/\/api.w.org\/{rel}","templated":true}]}}